HyperShear™ HPLC and UHPLC Mixers

  • Static Mixers are available in Standard HPLC, UHPLC, Biocompatible PEEK and In-Line Combo Series
  • Available for In-line, Binary and Ternary formats in 316 Stainless Steel
  • PEEK biocompatible is available
  • Reduce baseline noise, increase sensitivity and improve gradient accuracy
  • Ideal for microbore HPLC, UHPLC and LC/MS
  • Compact design is easily integrated into any HPLC and UHPLC system
  • Increased reaction efficiency for post column derivatization
  • Decreased mixing and delay volume without sacrificing mixing efficiency
  • Mixing volume optimization is easy with interchangeable mixer cartridges in most series
  • UHPLC mixers are available in volumes ranging from 0.5 µL to 1.5 mL and pressure up to 18,000 PSI
  • High Temperature rating above 40°C with Max 80°C is available for 0.5 μL to 1.5 mL for Standard HPLC (6,000 PSI)
  • High Temperature (Max 80°C) & Ultra High Pressure (12,000 PSI) is available for Micro Series (0.5 μL - 25 μL) 
  • Also we offer Dynamic Mixers

ASI manufactures a wide range of Static Mixers to solve the most demanding high pressure mixing problems.  ASI HyperShear Mixers incorporate a highly efficient cross-flow shearing mechanism which produces vortex shear mixing over a wide flow range. This mixing technology typically delivers between 25% to 200% better mixing efficiency compared to conventional packed bed or tortuous path mixers.  HyperShear Mixers are available in a variety of housing formats including: inline, binary, and ternary inlets. Mixers are constructed from 316 stainless steel with volumes ranging from 0.5 μL to 15.0 mL. or Biocompatible PEEK with volumes ranging from 0.5 μL to 1.5 mL.  Within a given mixer flow series, mixer cartridges are interchangeable.  The ability to swap mixer cartridges within a given mixer series makes selecting the optimum mixer volume easy and economical.  UHPLC mixers, In-Line Combo Series and Prep Flow Series (3.0 mL - 15 mL) are only sold as complete assemblies.

Mixer Brochure

ASI vs Competitor Comparison

Journal of Chromatography, ASI 250 μL Static Mixer  The application of ASI 250 µL mixer to neutralize an antibody – protein system